After cleansing and toning, gently place a patch under each eye with the wing pointing outward. Leave on for 20-30 minutes so the hydrogel melts and the actives absorb, then pat any remaining essence into skin and continue with the rest of your routine. Retinal beginners should start 2-3 times a week and build up to daily use as tolerated, and always finish with SPF in the morning since retinal increases sun sensitivity.